Metabolic Modelling and Synthetic Biology

Synthetic biology main purposes is to create novel biological functions and systems by combining biology with engineering. The workflow of the development of novel biological functions with synthetic biology is ideally linear which will be attainable with the quantitative engineering approach, high-quality predictive models, and libraries of well-characterized parts. In particular phases of synthetic biology workflow different types of metabolic models, mathematical representations of metabolism and its components, enzymes and metabolites, are useful.

  • Genome-scale modelling & flux balance analysis
  • In silico design of novel pathways
  • Signal transduction
  • Architecture of human metabolome
  • Computational data analysis in metabolomics
  • Metabolic flux analysis and metabolic models
  • Metabolic network simulation

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