Metabolic Modelling and Synthetic Biology

This aims to create novel biological functions and systems not found in nature by combining biology with engineering. The workflow of the development of novel cell factories with synthetic biology is ideally linear which will be attainable with the quantitative engineering approach, high-quality predictive models, and libraries of well-characterized parts. Different types of metabolic models, mathematical representations of metabolism and its components, enzymes and metabolites, are useful in particular phases of the synthetic biology workflow.

  • Genome-scale modelling & flux balance analysis
  • In silico design of novel pathways
  • Signal transduction
  • Architecture of human metabolome
  • Computational data analysis in metabolomics
  • Metabolic flux analysis and metabolic models
  • Metabolic network simulation

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