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Theme: Novel Trends in Metabolomics and Systems Biology

Eurometabolomics-2023

Eurometabolomics-2023

19^th International Conference on Metabolomics and Systems Biology scheduled to be held during April 17-18, 2023 at Rome, Italy. This is a wonderful opportunity for the participants from the Universities and Organizations to network with the eminent Scientists. The theme of the conference is “Novel Trends in Metabolomics and Systems Biology”

Euro Metabolomics 2023 will be a platform to investigate recent research and advancements that can be useful to the researchers. Metabolomics is a rapidly emerging field to identify and quantify cellular metabolites of a biological system at a particular point of time by using sophisticated analytical techniques. Most recent innovations covered in the conference are Metabolomic Modelling and Drug Design, Precision Medicine, NMR, LC-MS, GC-MS, Mass Spectrometry, UPLC, and Ion mobility spectrometry analytical methods, Targeted Metabolomics, Biomarker Metabolomics, Cancer Metabolomics, Metabolomic Profiling, Metabolomic Fingerprinting, Lipidomics, Data analysis using Systems Biology approach.

Why to Attend?

• Find out what’s new

• Meet experts & influencers face to face

• To present your ideas and work to others

• Networking for future collaborations

• The focus & energy of Like-Minded Individuals

• Fresh way of knowledge transfer

• Learn beyond your field or interest

• Meet, collaborate & get inspired

• Travel and extend your comfort zone

Targeted Audience

· Directors, Board Members, Presidents, Vice Presidents, Deans and Head of the Departments

· Metabolomics Researchers, Scientists, Faculties, Students

· Metabolomics Associations and Societies

· Medical Colleges

· Pharmaceutical Companies and Industries

· Medical Devices Manufacturing Companies

· Drug Manufacturing Companies and Industries

· Laboratory Technicians and Diagnostic Companies

· Business Entrepreneurs and Industrialists

· Training Institutes

· Software Developing Companies

· Data Management Companies

Young Research’s Awards at Euro Metabolomics 2023

Euro Metabolomics is intended to honor prestigious award for talented Young researchers, Scientists, Young Investigators, Post-Graduate students, Post-doctoral fellows, Trainees, Junior faculty in recognition of their outstanding contribution towards the conference theme. The Young Scientist Awards make every effort in providing a strong professional development opportunity for early career academicians by meeting experts to exchange and share their experiences on all aspects of Euro Metabolomics.

Young Research’s Awards at Euro Metabolomics for the Nomination:

Young Researcher Forum - Outstanding Masters/Ph.D./Post Doctorate thesis work Presentation and only 25 presentations acceptable at the Euro Metabolomics 2023

YRF Registration benefits:

· Young Scientist Award recognition certificate and memento to the winners

· Euro Metabolomics 2023 provides best Platform for your research through oral presentations.

· Learn about career improvement with all the latest technologies by networking.

· Provide an opportunity for research interaction and established senior investigators across the globe in the field Euro Metabolomics 2023.

· It is a great privilege for young researchers to learn about the research areas for expanding their research knowledge.

TRACK 1: Metabolomics

Metabolomics is the systematic study of the metabolome, the unique biochemical fingerprint of all cellular processes. It is an Omics technology that allows simultaneous, global, and comprehensive characterization of small molecules in a biological system. It is the large-scale study of small molecules within a mass range of 50 – 1500 Daltons (Da), commonly known as metabolites, within cells, bio fluids, tissues or organisms. These metabolites within biological samples under given genetic, nutritional or environmental conditions are known as metabolome.

America:

Metabolomics Society, NIH West Coast Metabolomics Center, Metabolomics Workbench; Sciex Metabolomics Community, North West Metabolomics research centre, Canadian Society for Systems Biology, Human Metabolome Technologies (HMT), The International Society for Systems Biology (ISSB), ISCB - International Society for Computational Biology, PhenoMeNal consortium, Canadian Society for Analytical Sciences and Spectroscopy, American Society for Biochemistry and Molecular Biology.

Europe:

Netherlands Metabolomics centre, Cambridge Metabolomics Forum, Metabolic Profiling Forum; MetaboHUB, Swedish Metabolomics Centre, Metabometrix, Association of Applied Biologist, British society for Immunology, Royal Society of Biology, Royal Society of Chemistry, Romanian society of Biochemistry and Molecular Biology, London International Youth Science Forum, Royal Society of Biology

Asia Pacific & Middle East:

Metabolomics Australia, Mass Spectrometry Society of Japan, Japanese Biochemistry Society, Molecular Biology Society of Japan, Taiwan Society for Biochemistry and Molecular Biology, Chinese Society of Biochemistry and Molecular Biology, New Zealand society of Biochemistry and Molecular Biology

TRACK 2: Systems Biology

Systems biology is the study of biological systems at a cellular, molecular and organism level, as an integrated and interacting network of genes, proteins and biochemical reactions which give rise to life. It will become main stream in biological sciences this century. It can be used to systematically at all levels, from molecules to entire systems and its integration into quantitative models to gain knowledge in order to make accurate simulation of biological processes possible. The technologies such as genomics, bioinformatics, proteomics, mathematical and computational models are used for predicting dynamical behaviour and quantitative measurements of the behaviour.

Related Association:

America:

NIH West Coast Metabolomics Center, Metabolomics Workbench; Sciex Metabolomics Community, North West Metabolomics research centre, Canadian Society for Systems Biology, Human Metabolome Technologies (HMT), The International Society for Systems Biology (ISSB), ISCB - International Society for Computational Biology, PhenoMeNal consortium, Canadian Society for Analytical Sciences and Spectroscopy, American Society for Biochemistry and Molecular Biology, Metabolomics Society

Europe:

Cambridge Metabolomics Forum, Metabolic Profiling Forum; MetaboHUB, Swedish Metabolomics Centre, Metabometrix, Association of Applied Biologist, British society for Immunology, Royal Society of Biology, Royal Society of Chemistry, Romanian society of Biochemistry and Molecular Biology, London International Youth Science Forum, Royal Society of Biology, Netherlands Metabolomics centre

Asia Pacific & Middle East:

Mass Spectrometry Society of Japan, Japanese Biochemistry Society, Molecular Biology Society of Japan, Taiwan Society for Biochemistry and Molecular Biology, Chinese Society of Biochemistry and Molecular Biology, New Zealand society of Biochemistry and Molecular Biology, Metabolomics Australia

TRACK 3: Metabolomics in Systems Biology

Metabolomics along with systems biology can be used to identify endogenous metabolites that modify protein expression. The main aim of Omics technologies is to reveal unexpected properties of biological systems by their nature. On behalf of metabolomics, gas and liquid chromatography coupled to mass spectrometry are well suited for coping with high sample numbers in reliable measurement times with respect to both technical accuracy and quantitation of small molecular weight metabolites. This prospective is a prerequisite for the analysis of dynamic systems. Accordingly, metabolomics is a key technology for systems biology.

America:

Metabolomics Workbench; Sciex Metabolomics Community, North West Metabolomics research centre, Canadian Society for Systems Biology, Human Metabolome Technologies (HMT), The International Society for Systems Biology (ISSB), ISCB - International Society for Computational Biology, PhenoMeNal consortium, Canadian Society for Analytical Sciences and Spectroscopy, American Society for Biochemistry and Molecular Biology, Metabolomics Society, NIH West Coast Metabolomics Center

Europe:

Metabolic Profiling Forum; MetaboHUB, Swedish Metabolomics Centre, Metabometrix, Association of Applied Biologist, British society for Immunology, Royal Society of Biology, Royal Society of Chemistry, Romanian society of Biochemistry and Molecular Biology, London International Youth Science Forum, Royal Society of Biology, Netherlands Metabolomics centre, Cambridge Metabolomics Forum.

Asia Pacific & Middle East:

Japanese Biochemistry Society, Molecular Biology Society of Japan, Taiwan Society for Biochemistry and Molecular Biology, Chinese Society of Biochemistry and Molecular Biology, New Zealand society of Biochemistry and Molecular Biology, Metabolomics Australia, Mass Spectrometry Society of Japan.

TRACK 4: Metabolic Modelling and Synthetic Biology

Synthetic biology main purposes is to create novel biological functions and systems by combining biology with engineering. The workflow of the development of novel biological functions with synthetic biology is ideally linear which will be attainable with the quantitative engineering approach, high-quality predictive models, and libraries of well-characterized parts. In particular phases of synthetic biology workflow different types of metabolic models, mathematical representations of metabolism and its components, enzymes and metabolites, are useful.

Related Association:

America:

Sciex Metabolomics Community, North West Metabolomics research centre, Canadian Society for Systems Biology, Human Metabolome Technologies (HMT), The International Society for Systems Biology (ISSB), ISCB - International Society for Computational Biology, PhenoMeNal consortium, Canadian Society for Analytical Sciences and Spectroscopy, American Society for Biochemistry and Molecular Biology, Metabolomics Society, NIH West Coast Metabolomics Center, Metabolomics Workbench

Europe:

MetaboHUB, Swedish Metabolomics Centre, Metabometrix, Association of Applied Biologist, British society for Immunology, Royal Society of Biology, Royal Society of Chemistry, Romanian society of Biochemistry and Molecular Biology, London International Youth Science Forum, Royal Society of Biology, Netherlands Metabolomics centre. Cambridge Metabolomics Forum, Metabolic Profiling Forum

Asia Pacific & Middle East:

Molecular Biology Society of Japan, Taiwan Society for Biochemistry and Molecular Biology, Chinese Society of Biochemistry and Molecular Biology, New Zealand society of Biochemistry and Molecular Biology, Metabolomics Australia, Mass Spectrometry Society of Japan, Japanese Biochemistry Society

TRACK 5: Computational Methodologies

Computational Biology is a rapidly emerging field, at the interface of computer science, arithmetic, physics and biology to study, analyse and understand complex biological systems by taking a corresponding integrated systems view using computational methodologies. The recent advances in computational methodologies are high throughput techniques and computational power. Computational systems biology provides a point of merging for genomics, proteomics, metabolomics and computational modelling and plays a key role in the fast progression of the evolving field by the outstanding developments in biology and computer science.

Related Association:

America:

North West Metabolomics research centre, Canadian Society for Systems Biology, Human Metabolome Technologies (HMT), The International Society for Systems Biology (ISSB), ISCB - International Society for Computational Biology, PhenoMeNal consortium, Canadian Society for Analytical Sciences and Spectroscopy, American Society for Biochemistry and Molecular Biology, Metabolomics Society, NIH West Coast Metabolomics Center, Metabolomics Workbench; Sciex Metabolomics Community

Europe:

Swedish Metabolomics Centre, Metabometrix, Association of Applied Biologist, British society for Immunology, Royal Society of Biology, Royal Society of Chemistry, Romanian society of Biochemistry and Molecular Biology, London International Youth Science Forum, Royal Society of Biology, Netherlands Metabolomics centre. Cambridge Metabolomics Forum, Metabolic Profiling Forum, MetaboHUB

Asia Pacific & Middle East:

Taiwan Society for Biochemistry and Molecular Biology, Chinese Society of Biochemistry and Molecular Biology, New Zealand society of Biochemistry and Molecular Biology, Metabolomics Australia, Mass Spectrometry Society of Japan, Japanese Biochemistry Society, Molecular Biology Society of Japan

TRACK 6: Plant and Environmental Metabolomics

Plant metabolomics is a recent research field that has gained increasing interest in the past few years and is applied for sub atomic level of the total metabolite and metabolome of plants under particular conditions. Metabolomics is applied for a better understanding the relation between genes and the biochemical composition of a plant tissue in response to its environment conditions and this information can be further used to assess gene function. The environmental metabolomics is use of metabolomics strategies to investigate the connections of life forms with their surroundings.

Related Association:

America:

Human Metabolome Technologies (HMT), The International Society for Systems Biology (ISSB), ISCB -International Society for Computational Biology, PhenoMeNal consortium, Canadian Society for Analytical Sciences and Spectroscopy, , Metabolomics Society, NIH West Coast Metabolomics Center, Metabolomics Workbench; Sciex Metabolomics Community, North West Metabolomics research centre, Canadian Society for Systems Biology, American Society for Biochemistry and Molecular Biology

Europe:

Association of Applied Biologist, British society for Immunology, Royal Society of Biology, Royal Society of Chemistry, Romanian society of Biochemistry and Molecular Biology, London International Youth Science Forum, Royal Society of Biology, Netherlands Metabolomics centre. Cambridge Metabolomics Forum, Metabolic Profiling Forum, MetaboHUB, Swedish Metabolomics Centre, Metabometrix

Asia Pacific & Middle East:

New Zealand society of Biochemistry and Molecular Biology, Metabolomics Australia, Mass Spectrometry Society of Japan, Japanese Biochemistry Society, Molecular Biology Society of Japan, Taiwan Society for Biochemistry and Molecular Biology, Chinese Society of Biochemistry and Molecular Biology

TRACK 7: Pharmaco-metabolomics

Pharmacometabolomics/Pharmacometabonomics is used to determibe the metabolic biomarkers that could potentially predict different responses of clinical drugs by identifying differential metabolites at baseline and correlating their variations with the therapeutic outcomes. Presently, Pharmacometabolomics is still in its infancy because most pharmacometabolomics studies are merely focused on revealing the correlation between baseline metabotypes which are influenced by factors such as diets, ages, drug intake and gut microbiota with drug responses or disease susceptibility to study and minimize the metabolic biases.

Related Association:

America:

American Society for Biochemistry and Molecular Biology, Metabolomics Society, NIH West Coast Metabolomics Center, Metabolomics Workbench; Sciex Metabolomics Community, North West Metabolomics research centre, Canadian Society for Systems Biology, Human Metabolome Technologies (HMT), The International Society for Systems Biology (ISSB), ISCB - International Society for Computational Biology, PhenoMeNal consortium, Canadian Society for Analytical Sciences and Spectroscopy

Europe:

Royal Society of Biology, Netherlands Metabolomics centre. Cambridge Metabolomics Forum, Metabolic Profiling Forum; MetaboHUB, Swedish Metabolomics Centre, Metabometrix, Association of Applied Biologist, British society for Immunology, Royal Society of Biology, Royal Society of Chemistry, Romanian society of Biochemistry and Molecular Biology, London International Youth Science Forum

Asia Pacific & Middle East:

TRACK 8: Nmr-based Metabolomics

NMR-based metabonomics categorises and provides information regarding organ-specific toxicity, monitor the onset and progression of toxicological effects, and identify biomarkers of toxicity. An upcoming challenge of metabolomics is to describe the cellular metabolome for purposes of understanding cellular functions. Such information is crucial if metabolomics is to provide a balancing dataset together with genomics and proteomics can be used to construct computer network models to describe cellular functions. NMR data are vastly reproducible and quantitative over a wide vigorous range and are unparalleled for determining structures of unknowns.

Related Association:

America:

Metabolomics Society, Metabolomics Workbench; Sciex Metabolomics Community, North West Metabolomics research centre, Canadian Society for Systems Biology, Human Metabolome Technologies (HMT), The International Society for Systems Biology (ISSB), ISCB - International Society for Computational Biology, PhenoMeNal consortium, Canadian Society for Analytical Sciences and Spectroscopy, , NIH West Coast Metabolomics Center, American Society for Biochemistry and Molecular Biology.

Europe:

Asia Pacific & Middle East:

Taiwan Society for Biochemistry and Molecular Biology, Metabolomics Australia, Mass Spectrometry Society of Japan, Japanese Biochemistry Society, Molecular Biology Society of Japan, Chinese Society of Biochemistry and Molecular Biology, New Zealand society of Biochemistry and Molecular Biology

TRACK 9: Mass Spectroscopy (Ms) based Metabolomics

Diverse analytical techniques are needed to achieve higher coverage of metabolites present within a biological system, which consists of a mass of molecules, having a variety of physical and chemical properties and existing as a dynamic range in biological samples. The application of mass spectrometry in metabolomics has increased exponentially since the discovery and development of electrospray ionization and matrix-assisted laser desorption ionization techniques.

Related Association:

America:

The International Society for Systems Biology (ISSB), ISCB - International Society for Computational Biology, Metabolomics Society, NIH West Coast Metabolomics Center, Metabolomics Workbench; Sciex Metabolomics Community, North West Metabolomics research centre, Canadian Society for Systems Biology, Human Metabolome Technologies (HMT), PhenoMeNal consortium, Canadian Society for Analytical Sciences and Spectroscopy, American Society for Biochemistry and Molecular Biology.

Europe:

Metabometrix, Association of Applied Biologist, Netherlands Metabolomics centre. Cambridge Metabolomics Forum, Metabolic Profiling Forum; MetaboHUB, Swedish Metabolomics Centre, British society for Immunology, Royal Society of Biology, Royal Society of Chemistry, Romanian society of Biochemistry and Molecular Biology, London International Youth Science Forum, Royal Society of Biology

Asia Pacific & Middle East:

Molecular Biology Society of Japan, Metabolomics Australia, Mass Spectrometry Society of Japan, Japanese Biochemistry Society, Taiwan Society for Biochemistry and Molecular Biology, Chinese Society of Biochemistry and Molecular Biology, New Zealand society of Biochemistry and Molecular Biology

TRACK 10: Metabolomics Approaches

Metabolomics Analytical approaches for can be categorized largely into two discrete groups targeted or untargeted. These approaches can further be segmented as metabolic profiling, using an untargeted approach or metabolite identification and quantitation using a targeted approach. A diverse terminology for the definition of metabolic approaches has been used by various metabolomic research areas.

Targeted metabolomics measures predefined metabolites of interest in samples which requires prior knowledge of associations between metabolite concentration and disease states. This technique is useful for the determination of absolute metabolite concentrations as well as easier identification of specific metabolites.
Untargeted metabolomic measures metabolites associated with a disease state are determined between different samples which does not requires prior knowledge of associations between metabolite concentration and disease states. The primary aim is to identify new metabolic compounds or changes that have not previously been associated with disease.

Related Association:

America:

The International Society for Systems Biology (ISSB), ISCB - International Society for Computational Biology, PhenoMeNal consortium, Canadian Society for Analytical Sciences and Spectroscopy, , Metabolomics Society, NIH West Coast Metabolomics Center, Metabolomics Workbench; Sciex Metabolomics Community, North West Metabolomics research centre, Canadian Society for Systems Biology, Human Metabolome Technologies (HMT), American Society for Biochemistry and Molecular Biology

Europe:

Royal Society of Biology, Royal Society of Chemistry, Romanian society of Biochemistry and Molecular Biology, London International Youth Science Forum, Royal Society of Biology, Netherlands Metabolomics centre. Cambridge Metabolomics Forum, Metabolic Profiling Forum; MetaboHUB, Swedish Metabolomics Centre, Metabometrix, Association of Applied Biologist, British society for Immunology

Asia Pacific & Middle East:

TRACK 11: Analytical Techniques in Metabolomics

The recent analytical platforms based on mass spectrometry and nuclear magnetic resonance has enabled separation, characterization, detection, and quantification of such chemically diverse structures. This continued development of these analytical platforms will accelerate extensive use and combination of metabolomics into systems biology

Metabolic Profiling: Metabolic profiling is defined as the identification and quantification of a selected number of pre-defined metabolites which are related to a specific metabolic pathway.
Metabolic Fingerprinting: Analysis of unbiased, rapid, global analysis of samples to provide sample classification is oriented towards defining clinically relevant differences rather than identifying all the molecules present in a sample. These metabolic fingerprints can be used to distinguish between different disease phenotypes and to predict a drug's effectiveness and toxicity.
Nuclear Magnetic Resonance: NMR-based metabonomics provides a means to categorize organ-specific toxicity, monitor the onset of action and progression of toxicological effects, and identify biomarkers of toxicity. It is used to describe the cellular metabolome for purposes of understanding cellular functions.
Mass Spectrometry: The application of mass spectrometry in metabolomics has increased exponentially since the discovery and development of electrospray ionization and matrix-assisted laser desorption ionization techniques.
Gas Chromatography-Mass Spectrometry
Liquid Chromatography-Mass Spectrometry
Capillary Electrophoresis-Mass Spectrometry
Fourier-Transform Mass Spectrometry: Among all the analytical platforms, which requires complementary analytical platforms for extensive coverage, atmospheric pressure ionization Fourier transform mass spectrometry (FT/MS) instruments are popular because they provide accurate mass measurements of ppm along with sub-ppm errors. It also high and ultra-high resolving power.

Related Association:

America:

Europe:

Netherlands Metabolomics centre. Cambridge Metabolomics Forum, Metabolic Profiling Forum; MetaboHUB, Swedish Metabolomics Centre, Metabometrix, Association of Applied Biologist, British society for Immunology, Royal Society of Biology, Royal Society of Chemistry, Romanian society of Biochemistry and Molecular Biology, London International Youth Science Forum, Royal Society of Biology

Asia Pacific & Middle East:

TRACK 12: Metabolomics Applications

Metabolomics is a recent area which potentials to contribute expressively to the characterization of various disease phenotypes and to the identification of personal metabolic features that can predict response to therapies and some of which are Microbiology, plants and medical science

Pharmacology & Pre-Clinical Drug Trials
Toxicology
Transplant Monitoring
New-Born Screening
Clinical Chemistry
Tool for Functional Genomics
Screening Services
Biomarker Search / Identification
Companion Diagnostics
Drug Development Optimization
LC/MS/MS Analysis
Combinatorics in Metabolomics
DATA Analysis & Interpretation

Related Association:

America:

The International Society for Systems Biology (ISSB), ISCB - International Society for Computational Biology, PhenoMeNal consortium, Canadian Society for Analytical Sciences and Spectroscopy,American Society for Biochemistry and Molecular Biology, Metabolomics Society, NIH West Coast Metabolomics Center, Metabolomics Workbench; Sciex Metabolomics Community, North West Metabolomics research centre, Canadian Society for Systems Biology, Human Metabolome Technologies (HMT),

Europe:

Association of Applied Biologist, British society for Immunology, Royal Society of Biology, Royal Society of Chemistry, Romanian society of Biochemistry and Molecular Biology, London International Youth Science Forum, Royal Society of Biology, Netherlands Metabolomics centre. Cambridge Metabolomics Forum, Metabolic Profiling Forum; MetaboHUB, Swedish Metabolomics Centre, Metabometrix.

Asia Pacific & Middle East:

Taiwan Society for Biochemistry and Molecular Biology, Chinese Society of Biochemistry and Molecular Biology, Metabolomics Australia, Mass Spectrometry Society of Japan, Japanese Biochemistry Society, Molecular Biology Society of Japan, New Zealand society of Biochemistry and Molecular Biology

TRACK 13: Metabolomics in the field Of Oncology / Cancer Metabolomic

The application of metabolomics in the field of cancer research has led to the progress of metabolism in development of cancer. In the past ten years, the re-discovery of cancer as a metabolic disorder has happened due to the increased accessibility of metabolomics, identification of cancer metabolite biomarkers and the discovery of oncometabolites.

Biomarker in cancer diagnosis, prognosis, & therapeutic response Screening tool
Detection of micro metastases
As both predictive & pharmacodynamics marker of drug effect including search for new drugs
In Nutrigenomics it is used to see the effect of diet on cancer prevention and its response to treatment
As translational research tool which can provide link between clinical & laboratory
Molecular analyses of cancers to know the information about the mechanisms of initiation, progression & provide foundation for clinical tests

Related Association:

America:

American Society for Biochemistry and Molecular Biology,Metabolomics Society,NIH West Coast Metabolomics Center, Metabolomics Workbench; Sciex Metabolomics Community, North West Metabolomics research centre, Canadian Society for Systems Biology, Human Metabolome Technologies (HMT), The International Society for Systems Biology (ISSB), ISCB - International Society for Computational Biology, PhenoMeNal consortium, Canadian Society for Analytical Sciences and Spectroscopy

Europe:

Asia Pacific & Middle East:

TRACK 14: Metabolomics in Precision Medicine / Personalised Medicine

Precision medicine is developing as a strategy to alter medical treatment to a small group or even discrete patients based on their genetics, environment and lifestyle. The increasing advance in metabolomics technology identifies the enormous potential of its application in personalized medicine. Merging metabolomics with genomics, transcriptomics, and proteomics studies will result in a significantly improved understanding of the disease mechanisms and the pathophysiology of the target clinical phenotype. The final goal of personalized medicine is to enable clinicians to prescribe the right medicine to the right patient at the right time with maximum efficacy and minimal toxicity.

Related Association:

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TRACK 15: Metabolomics in Discovering Biomarkers

Over a period of time, metabolomics studies have identified several relevant biomarkers involved in complex clinical phenotypes using diverse biological systems. Metabolomics can be applied to identify biomarkers related to the perturbation being investigated and these biomarkers can be used to develop personalized prognostic, diagnostic, and treatment approaches. These discovered biomarkers can also be applied further in monitoring of disease progression, treatment efficacy, predisposition to drug-related side effects, and potential relapse.

Related Association:

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TRACK 16: Metabolomics in Drug Discovery

Metabolomics is being used in Drug Discovery and in development from lead compound discovery to post approval drug surveillance. Metabolomics can help in finding potential new sites for therapeutic intervention by identifying metabolic changes. Metabolomics can provide activity information about possible novel drugs and drug scaffolds, indicate interesting targets for drug development and suggest binding partners of compounds. Furthermore, metabolomics can be used for the discovery of novel natural products and in drug development. Metabolomics can enhance the discovery and testing of new drugs and provide insight into the on- and off-target effects of drugs.

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TRACK 17: Metabolomics in detection of Chemotoxicity

Chemotherapy drugs capable to cause significant, irreversible, life threatening organ damage which is distressing for patients and might affect the optimal delivery of treatment. Various studies have predicted the risk factors for drug induced organ damage because of lack of biomarker to pick-up these changes in early phase causes potential morbidity and mortality. Metabolomics can address relation between gene, drugs environment and thus increase our ability to predict individual variation in drug response phenotypes.

Related Association:

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TRACK 18: Metabolomics in Nutrition Research

Nutritional metabolomics is rapidly developing small molecule chemical profiling to support integration of diet and nutrition in complex bio systems research. Foodomics is a new discipline that studies food and nutrition domains through the application of advanced Omics technologies which include the genomic, transcriptomic, proteomic, and metabolomics study of foods for compound profiling, authenticity, and biomarker detection related to food quality or safety, the development of new transgenic foods, food contaminants, and whole toxicity studies and the new investigations on food bioactivity, food effects on human health.

Related Association:

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Asia Pacific & Middle East:

TRACK 19: Metabolomics in Pharmaceutics

In field of pharmaceuticals, metabolomics is turning into an inevitably mainstream instrument for life sciences as it is generally fast and also precise procedure this can be connected with either a particular centre or in a international way to discover new learning about organic frameworks.

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TRACK 20: Metabolomic in the field of Paediatric Medicine

In paediatric medicine, the potential applications for metabolomics a highly informative technique that can also be used on non-invasively collected samples. NMR- based Metabolomics might serve as a promising approach for the diagnosis and prediction of mortality in septic shock in a paediatric population and that quantitative metabolomics methods can be applied in the clinical evaluations of paediatric septic shock.

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TRACK21: Metabolomics in various Diseases

Metabolomics is a novel approach that potentials to enable the detection of states of disease, to categories the patients based on biochemical profiles and to monitor disease progression. Metabolomic analysis may also be able to orient the choice of therapy, identify responders and predict toxicity, paving the way to a customized therapy.

Metabolomics in Neuropsychiatric Disorders: Metabolomics approach has revealed new opportunities in diagnostics of devastating disorders like neuropsychiatric disorders. Metabolomics-based technologies have the prospective to map early biochemical fluctuations in disease and hence provide a prospect to develop predictive biomarkers that can be used as indicators of pathological deviations prior to development of clinical symptoms of neuropsychiatric disorders.
Metabolomics in Metabolic Disorders: Metabolomics uses in the identification of metabolites not previously associated with metabolic traits highlight the importance and agitations of particular metabolites and advances novel strategies to prevent type 2 diabetes and illustrate biomarkers that can help with early detection, disease progression and therapeutic response. Consequently, the use of metabolomics in this area will continue to grow in basic research science and clinical medical applications.
Metabolomics in Cardiovascular Diseases: Cardiovascular diseases are the leading causes of death worldwide. There is a need for the development of particular diagnostic techniques, more effective therapeutic procedures as well as drugs, which can decrease the mortality rate in the course of CVDs. Metabolomic technologies may serve as diagnostic and/or prognostic tools that have the potential to significantly alter the management of CVD. Metabolomics can assist in the interpretation of perturbed metabolic processes, and improves our ability to understand the pathology of ischemic heart disease, atherosclerosis, and heart failure.
Metabolomic studies in Rheumatoid Arthritis: Metabolites from the nucleic acid and oxidative stress pathways are potential biomarkers for rheumatoid arthritis pathology. Metabolite profiles in rheumatoid arthritis plasma are associated to disease activity and treatment response. Metabolomic studies confirm the hypoxic nature of the inflamed synovial joint in rheumatoid arthritis.
Metabolomic studies in Systemic Lupus Erythematous: Low histidine levels have been identified in the serum of systemic lupus erythematosus (SLE) and RA could explain the increased incidence of cardiovascular disease observed for both rheumatic diseases. Taurine and citrate levels in the SLE urine metabolome have potential utility as biomarkers for SLE nephritis subtype discrimination.
studies in Ankylosing Spondylitis: Metabolite levels in serum reflect an alteration in the vitamin D3 metabolism in ankylosing spondylitis. Metabolomic studies of patients and controls identified reduced levels of tryptophan in ankylosing spondylitis, probably due to IFN-γ expression in the disease.
Metabolomic studies in Psoriatic Arthritis: To date, no studies have directly compared psoriatic arthritis and psoriasis metabolomics profiles. The urine metabolome in psoriatic arthritis is correlated with the changes in disease activity induced by anti-TNF treatment.
Metabolomic studies in Osteoarthritis: The prediction model built from the urine metabolite concentrations correlates significantly with the Kellgren–Lawrence radiographic scores of osteoarthritis severity. The valine/histidine and the xleucine(isoleucine and leucine)/histidine ratios are potential biomarkers of the development of knee osteoarthritis.
Metabolomic studies in Gouty Arthritis: Uric acid is not a sufficiently informative biomarker of gouty arthritis and additional markers must be identified. Gouty arthritis also expresses the common core of serum metabolites found in other prevalent arthritis. This common set of metabolites could be useful for the development of improved diagnostic systems.
Metabolomics in Nephrology: The application of metabolomics in nephrology research has expanded from the initial analyses of uraemia to include both cross-sectional and longitudinal studies of earlier stages of kidney disease. Chronic kidney disease, Diabetic nephropathy, Acute kidney injury, Kidney transplantation and End-stage renal disease

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TRACK 22: Metabolomics in Metabolic Engineering

Metabolic engineering is the use of genetic engineering to modify the metabolism of an organism which deals with the measurement of metabolic fluxes and elucidation of their control as determinants of metabolic function and cell physiology. An innovative aspect of metabolic engineering is that it departs from the outdated reductionist paradigm of cellular metabolism, taking instead a holistic view. Metabolic engineering is appropriate as a framework for the analysis of genome wide differential gene expression data, in combination with data on protein content and in vivo metabolic fluxes. The main aim of metabolic engineering is to manipulate metabolite production.

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TRACK 23: Transcriptomics and Proteomics

The transcriptomics refers to study of transcriptome, which is a dynamic levels of RNA transcripts vary during response to certain conditions in the cell or in different developmental stages of the cell. RNA- sequencing or Transcriptome sequencing is a next-generation sequencing (NGS)-based approach for RNA profiling and analysis by measuring the transcriptomic profiles through microarrays, RNA-seq etc... Proteomics refers to study of large-scale proteomes, which is the set of proteins produced in an organism or biological environment. One of the important objectives of Systems biology is to understand the regulation of cell behaviour by measuring the proteomic profiles through techniques such as gel electrophoresis and mass spectrometry.

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TRACK 24: Lipidomics

Lipidomics is an increasing field with plentiful applications. For investigating different cell types ESI mass spectroscopy is used. Identification of lipid composition and quantification of cellular lipids gives us details about the lipid related pathway which also helps in identification of metabolic pathways and the effected enzymes. The need for bioinformatics is to manage and integrate the experimental data in various aspects, such as, for lipid classification, ontologies, database design, analysis, and visual display and play diverse roles in human physiology.

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Scope and Importance:

Metabolomics is the quantitative and qualitative study of small molecules. It is said to be an important technique in systems biology. The purposes of metabolomics is accurate detection of disease, such as inflammation, necrosis, estimation of toxicity in newly designed drugs, Alzheimer’s, drug testing and interpreting biochemical pathways. Greater than 95% of clinical diagnostic assays tests are for small molecules. From pre-existing metabolites, 50% of the drugs are derived from known small molecule drugs.

Metabolomics Market Analysis:

The global metabolomics market is expected to grow at a CAGR of 26% from 2016 to 2021 to reach USD 3.53 Billion by 2021. The metabolomics market has significant growth mainly due to the increasing necessity for accurate diagnosis of diseases, development of innovative technologies, and increasing demand for precision medicine.

Europe is the second largest Market in the world with a share of ~38% of the global market. The presence of a large number of analytical equipment manufacturers has contributed significantly to the European metabolomics market. The APAC market is expected to grow at a CAGR of 23% during the forecast period.

Target Audience:

Directors for the Companies
Business Delegates
Investigators
Professors
Scientists
Research and Diagnostic Laboratories

Major Metabolomics Related Associations in Europe:

Association of Applied Biologist
British Society for Immunology
UCL Systems Biology
Royal Society of Biology
United Kingdom Systems Society

Metabolomics and Systems Biology Related Associations Worldwide:

Metabolomics Workbench
Metabolomics Society
Netherlands Metabolomics Center
Cambridge Metabolomics Forum
Metabolic Profiling Forum
Sciex Metabolomics Community
MetaboHUB
PhenoMeNal consortium
The International Society for Systems Biology (ISSB)
ISCB - International Society for Computational Biology
Canadian Society for Systems Biology
Society for Systems Biology & Translational Research
Institute of Molecular Systems Biology
Munich Systems Biology Forum
Centre for Complex Biological Systems.
Pharmacometabolomics Community (ASCPT)

Major Companies related to Metabolomics:

Metabolon, Inc.
Agilent Technologies
Thermo Fisher Scientific
Danaher Corporation
Bruker Corporation
Waters Corporation
Shimadzu Corporation

Conference Highlights

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Conference Date	April 17-18, 2023
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All accepted abstracts will be published in respective Our International Journals.

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19^th International Conference on Metabolomics & Systems Biology April 17-18, 2023 Rome, Italy

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Eurometabolomics-2023

Conference Highlights

To Collaborate Scientific Professionals around the World

Useful Links

Special Issues