Metabolomics in Detection of Chemotoxicity

Chemotherapy drugs capable to cause significant, irreversible, life threatening organ damage which is distressing for patients and might affect the optimal delivery of treatment. Various studies have predicted the risk factors for drug induced organ damage because of lack of biomarker to pick-up these changes in early phase causes potential morbidity and mortality. Metabolomics can address relation between gene, drugs environment and thus increase our ability to predict individual variation in drug response phenotypes.